Grafted chitosan nanogel with 3,4-methylenedioxycinnamic acid: synthesis, characterization and application in the encapsulation of monoterpenes with antifungal properties
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS(2024)
Abstract
Herein, a novel grafted chitosan nanogel with 3,4-methylenedioxycinnamic acid was carried out aiming at the encapsulation of the monoterpenes carvacrol and thymol, with the purpose of developing a material that can be used in the control of the fungus Microsporum canis. The nanogel encapsulation efficiency showed an encapsulation capacity of 12.9% carvacrol and 13.3% thymol. When in an aqueous medium the nanogel with the respective encapsulated monoterpene oils was able to form stable nanoparticles. The nanogels chitosan-g-3,4-methylenedioxycinnamic acid-carvacrol and chitosan-g-3,4-methylenedioxycinnamic acid-thymol showed antifungal potential against the fungus Microsporum canis, being able to inhibit mycelial growth by 100.00 and 93.13%, respectively.
MoreTranslated text
Key words
Carvacrol,chitosan,dermatophytosis,Microsporum canis,nanogel,thymol
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined