Successful treatment with atezolizumab combination chemotherapy in a patient with high-grade fetal adenocarcinoma of the lung: A case report
THORACIC CANCER(2023)
Abstract
High-grade fetal lung adenocarcinoma (H-FLAC) is a rare tumor, with little known of its response to chemotherapy with or without an immune checkpoint inhibitor or of its molecular profile. We report the first case of a 56-year-old man with stage IV H-FLAC who was successfully treated with carboplatin plus nab-paclitaxel in combination with atezolizumab. In addition, the tumor was found to be positive for amplification of the human epidermal growth factor receptor 2 gene.
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Key words
atezolizumab,case report,high-grade fetal lung adenocarcinoma (H-FLAC),human epidermal growth factor receptor 2 (HER2,ERBB2),immunotherapy
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