Project-Based Learning in Green Electrochemistry for Undergraduates: An Efficient Synthesis Route of a Natural Product

Project-based learning is widely used in organic laboratories. This goal-oriented and inquiry-based learning model complements student-centered training. Such models focus on complicated issues or real-world problems on the frontier of chemistry. Students progress through three project phases: preproject, during the project, and postproject. Herein, we combined organic synthesis, electrochemistry, and green chemistry to improve students' understanding of organic reactions and mechanisms and exposed them to a new method of organic synthesis, which is electrochemistry. Moreover, we integrated the concept of green chemistry into the study of organic chemistry, and student assessment indicated substantial improvement in the understanding of this concept. Students designed a simple electrochemical reactor and accomplished the synthesis of (+/-)-muscone. Meanwhile, student competencies were comprehensively improved. The project included a literature review, experimental procedures, and essay writing. Overall, responses from students regarding the project experience were highly affirming.