Antibacterial surface coatings of fracture fixation implants

Infection after internal fixation of fractures is one of its most common complications, which can lead to delayed fracture healing, non-union of fractures and even bone infection and osteomyelitis, causing a heavy burden to patients' families and society. In recent years, based on the concept of topical antimicrobial agents, scholars have proposed the method of antimicrobial coating on the material surfaces for internal fixation to treat and prevent postoperative infections associated with internal fixation. The antimicrobial mechanisms of surface coatings can be broadly classified into 3 categories, including antiadhesive coatings, silver (Ag) ion coatings, and antibiotic coatings. In this study, their advantages and disadvantages are described in detail to provide a IP: 84624710 On: Wed 14 Dec 2022 07:24:33 novel insight and theoretical basisfrCopyright:the improvmetAmerican Scof eficantimicroial Publisherscoatings in the future. e vered