Comprehensive landscape of the IPAF inflammasomes in pan-cancer: A bulk omics research and single-cell sequencing validation.

Chen-Cheng Dong,Qiu-Huan Zhang, Yan Zhang,Yujie Zhang,Hanyi Ruan,Tianyu Qin,Jie-Hua Zhao,Guo Wu,Zhou Zhu,Jian-Rong Yang

Computers in biology and medicine（2023）

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摘要

A pan-cancer analysis of IPAF inflammasome in various tumors was performed. The results highlight the potential value of IPAF inflammasome in response to immunotherapy in patients and provide a new direction for future immunotherapy.

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关键词

IPAF inflammasomes,Immunotherapy,Pan-cancer,Single-cell transcriptome sequencing,Tumor microenvironment

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