Lower T cell response against SARS-CoV-2 variants of concern after mRNA vaccine and risk of breakthrough infections in people with HIV.

José L Casado,Pilar Vizcarra, Sara Martín-Colmenarejo, Judith Del Pino, Sandra Gomez-Maldonado,Adrían Martín-Hondarza,Alejandro Vallejo

AIDS (London, England)(2023)

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Abstract
A blunted T-cell response against Delta and Omicron variant is observed in PWH who received two doses of mRNA vaccine. This lower immune response is associated with breakthrough SARS-CoV-2 infections.
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Key words
HIV, immune response, infections, omicron, SARS-CoV-2, vaccine
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