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Analysis of serum exosome microRNAs in the rat model of chronic obstructive pulmonary disease.

Chao Ouyang,Wenjun Wang,Dengfeng Wu,Wei Wang,Xiaoqun Ye, Qing Yang

American journal of translational research（2023）

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Abstract
The expression of miR-185-5p and miR-182-5p was down-regulated in serum-derived exosomes and lung tissues of COPD rats, indicating that these two miRNAs might be involved in the development of COPD and might serve as potential biomarkers for the diagnosis of COPD.
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Key words
Chronic obstructive pulmonary disease (COPD),bioinformatic analysis,exosomes,microRNA
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