Safety, Feasibility, and Potential Clinical Efficacy of 40 Hz Invisible Spectral Flicker versus Placebo in Patients with Mild-to-Moderate Alzheimer's Disease: A Randomized, Placebo-Controlled, Double-Blinded, Pilot Study.

Mikkel Pejstrup Agger,Else Rubæk Danielsen,Marcus Schultz Carstensen,N Mai Nguyen, Maibritt Horning,Mark Alexander Henney, Christopher Boe Ravn Jensen,Anders Ohlhues Baandrup,Troels Wesenberg Kjær,Kristoffer Hougaard Madsen,Kamilla Miskowiak,Paul Michael Petersen,Peter Høgh

Journal of Alzheimer's disease : JAD（2023）

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摘要

Treatment with 40 Hz ISF offers no significant safety or adherence concerns. Potential impact on secondary outcomes must be tested in larger scale clinical trials.

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关键词

40 Hz,Alzheimer’s disease,gamma entrainment,invisible spectral flicker,light-based neurostimulation

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