The association between trauma exposure, polygenic risk and individual depression symptoms

Jackson G Thorp,Zachary F Gerring,Lucía Colodro-Conde,Enda M Byrne,Sarah E Medland,Christel M Middeldorp,Eske M Derks

Psychiatry Research（2023）

引用 2|浏览22

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摘要

•Depression genetic risk interacts with trauma exposure to increase risk for depression.•Genetic risk and trauma are differentially associated with individual depression symptoms.•Suicidal ideation, low self- esteem, and atypical neurovegetative symptoms are most strongly associated.

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关键词

Depression,Symptoms,Trauma,Heterogeneity,Polygenic risk

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