Abdominal transplantation of pancreatic islets to protect against type 1 diabetes
NATURE METABOLISM（2023）
摘要
Human pluripotent stem cell-derived pancreatic islets (PSC-islets) hold promise in type I diabetes treatment, although their delivery is a challenge. We describe a new abdominal infusion transplantation protocol that enables the survival, maturation and maintenance of functional PSC-islets in diabetic monkeys.
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