The challenges and opportunities of scRNA-seq in COVID-19 research and clinical translation

Wendao Liu,Xiaohua Ye,Zhiqiang An,Zhongming Zhao

VIROLOGY JOURNAL（2022）

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摘要

The application of single-cell RNA sequencing in COVID-19 research has greatly improved our understanding of COVID-19 pathogenesis and immunological characteristics. In this commentary, we discuss the current challenges, limitations, and perspectives in harnessing the power of single-cell RNA sequencing to accelerate both basic research and therapeutic development for COVID-19 and other emerging infectious diseases.

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关键词

COVID-19,SARS-CoV-2,Single-cell RNA sequencing,COVID-19 sequela,Single-cell VDJ sequencing

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