Fast and label-free automated detection of microsatellite status in early colon cancer using artificial intelligence integrated infrared imaging.

Klaus Gerwert,Stephanie Schörner,Frederik Großerueschkamp,Anna-Lena Kraeft,David Schuhmacher,Carlo Sternemann,Inke S Feder,Sarah Wisser,Celine Lugnier,Dirk Arnold,Christian Teschendorf,Lothar Mueller,Nina Timmesfeld,Axel Mosig,Anke Reinacher-Schick,Andrea Tannapfel

European journal of cancer (Oxford, England : 1990)（2023）

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摘要

Our novel label-free digital pathology approach accurately and rapidly classifies MSI vs. MSS. The tissue sections analysed were not processed leaving the sample unmodified for subsequent analyses. Our approach demonstrates an AI-based decision support tool potentially driving improved patient stratification and precision oncology in the future.

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关键词

Artificial intelligence,Colon cancer,Convolutional neural networks,Deep learning,Infrared imaging,Label-free,Microsatellite instability

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