Extracellular Vesicle-microRNAs as Diagnostic Biomarkers in Preterm Neonates
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES(2023)
Abstract
Neonates born prematurely (<37 weeks of gestation) are at a significantly increased risk of developing inflammatory conditions associated with high mortality rates, including necrotizing enterocolitis, bronchopulmonary dysplasia, and hypoxic-ischemic brain damage. Recently, research has focused on characterizing the content of extracellular vesicles (EVs), particularly microRNAs (miRNAs), for diagnostic use. Here, we describe the most recent work on EVs-miRNAs biomarkers discovery for conditions that commonly affect premature neonates.
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Key words
neonate,prematurity,bronchopulmonary dysplasia,necrotizing enterocolitis,hypoxic-ischemic brain damage,extracellular vesicles,miRNA,biomarkers
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