Long-Term Seizure Freedom, Resolution of Epilepsy and Perceived Life Changes in Drug Resistant Temporal Lobe Epilepsy With Hippocampal Sclerosis: Comparison of Surgical Versus Medical Management.

Sita Jayalakshmi, Sindhu Vasireddy,Jala Sireesha,Sudhindra Vooturi,Anuja Patil,Sai Sirisha,Rammohan Vadapalli, Y B V K Chandrasekhar,Manas Panigrahi

Neurosurgery（2023）

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Abstract

Surgery for drug-resistant TLE-HS was associated with higher rate of long-term seizure-freedom, resolution of epilepsy, and reduction of anti-seizure medications with improvement in perceived life changes compared with best medical management. The presence of an aura was predictor for resolution of epilepsy while APOS and an abnormal postoperative EEG were predictors of persistent seizures.

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Key words

Epilepsy surgery, Hippocampal sclerosis, Life changes, Seizure freedom, Temporal lobe epilepsy

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