Determining the optimal initial dose for Japanese patients with nocturnal polyuria using an initial dose of desmopressin 50 μg.

Hirofumi Kurose,Keisuke Komiya,Naoyuki Ogasawara,Kosuke Ueda,Katsuaki Chikui,Kiyoaki Nishihara,Makoto Nakiri,Mitsunori Matsuo,Shigetaka Suekane,Tsukasa Igawa

Lower urinary tract symptoms（2023）

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摘要

Our study suggests that an initial dose of 50 μg is more effective than a uniformly minimum dose based on factors such as age and physique. Furthermore, a high continuation rate can be achieved by appropriately reducing the dose, if adverse events occur.

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desmopressin,hyponatremia,nocturnal polyuria,optimal initial dose,safety

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