Weight loss by calorie restriction does not alter appetite-regulating gut hormone responses from perfused rat small intestine.

Marina K Gerstenberg,Daniel B Andersen,Lola Torz,Carlos M Castorena,Angie L Bookout,Bolette Hartmann,Jens F Rehfeld,Natalia Petersen,Jens J Holst,Rune E Kuhre

Acta physiologica (Oxford, England)（2023）

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摘要

These data suggest that the attenuated postprandial responses of GLP-1, as well as reduced responses of other appetite-inhibiting gut hormones, in people living with obesity may persist after weight loss and may contribute to their susceptibility for weight regain.

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enteroendocrine function,gut hormone secretion,perfused rat small intestine,weight loss

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