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Does the VDR gene polymorphism influence the efficacy of denosumab therapy in postmenopausal osteoporosis?

Anna Wawrzyniak,Marzena Skrzypczak-Zielińska,Michał Michalak,Marta Kaczmarek-Ryś,Alicja Ewa Ratajczak,Anna Maria Rychter,Kinga Skoracka,Michalina Marcinkowska,Ryszard Słomski,Agnieszka Dobrowolska,Iwona Krela-Kaźmierczak

Frontiers in endocrinology（2022）

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Abstract
BB and Bb genotypes of the polymorphism of the gene determine higher DXA parameter values both before and after one-year denosumab therapy in postmenopausal women with osteoporosis.
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Key words
VDR gene polymorphism,bone fracture,denosumab therapy,osteoporosis,postmenopausal osteoporosis
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