Complement activation profiles in anti-acetylcholine receptor positive myasthenia gravis.

Frauke Stascheit,Omar Chuquisana,Christian W Keller,Philip Alexander Ambrose,Sarah Hoffmann,Catharina C Gross,Sophie Lehnerer,Heinz Wiendl,Nick Willcox,Andreas Meisel,Jan D Lünemann

European journal of neurology（2023）

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摘要

Markers indicative of complement activation are prominently increased in patients with AChR-Ab MG despite standard immunosuppressive therapies. Complement inhibition proximal to C5 cleavage should be explored for its potential therapeutic benefits in AChR-Ab MG.

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关键词

acetylcholine receptor,antibodies,biomarker,complement activation,myasthenia gravis

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