Concurrent immunotherapy and re-irradiation utilizing stereotactic body radiotherapy for recurrent high-grade gliomas.

Sean S Mahase,Michelle Roytman,Diana Roth O'Brien,Jana Ivanidze,Theodore H Schwartz,Susan C Pannullo,Rohan Ramakrishna,Rajiv S Magge,Nicholas Williams,Howard A Fine,Gloria Chia-Yi Chiang,Jonathan P S Knisely

Cancer reports (Hoboken, N.J.)（2023）

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摘要

In this heavily pretreated cohort, ICI with re-irradiation utilizing SBRT was well tolerated. Prospective studies are warranted to evaluate potential therapeutic benefits to re-irradiation with ICI + SBRT in rHGG.

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关键词

immune checkpoint inhibitor,nivolumab,pembrolizumab,recurrent high-grade glioma,stereotactic body radiotherapy

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