Discovery of a novel, liver-targeted thyroid hormone receptor-β agonist, CS271011, in the treatment of lipid metabolism disorders.
Frontiers in endocrinology(2023)
Abstract
CS271011 is a potent and liver-targeted THR-β agonist for treating lipid metabolism disorders.
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Key words
Resmetirom,dyslipidaemia,steatosis,thyroid hormone receptor,triglycerides
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