Multiple pathways of SARS-CoV-2 nosocomial transmission uncovered by integrated genomic and epidemiological analyses during the second wave of the COVID-19 pandemic in the UK.

Kate F Cook,Angela H Beckett,Sharon Glaysher,Salman Goudarzi,Christopher Fearn,Katie F Loveson,Scott Elliott, Sarah Wyllie, Allyson Lloyd,Kelly Bicknell,Sally Lumley,Anoop J Chauhan,Samuel C Robson

Frontiers in cellular and infection microbiology（2022）

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摘要

These analyses have highlighted the importance of control measures such as regular testing, rapid lateral flow testing alongside polymerase chain reaction (PCR) testing, isolation of positive patients in the emergency department (where possible), and physical distancing of patient beds on hospital wards to minimize nosocomial transmission of infectious diseases such as COVID-19.

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COVID-19,Oxford Nanopore Technologies (ONT),SARS-CoV-2,alpha variant,hospital-acquired infection,nosocomial infection,transmission dynamics,whole genome sequencing (WGS)

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