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STAT2/Caspase3 in the diagnosis and treatment of psoriasis.

Zhibing Fu,Yi He,Lihua Gao,Xiaoliang Tong, Lu Zhou,Jinrong Zeng

European journal of clinical investigation（2023）

Cited 2|Views7
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Abstract
In summary, STAT2 overexpression contributes to psoriasis progression by regulating Capase3 phosphorylation to induce excessive apoptosis of keratinocytes. Meanwhile, STAT2 and Capase3 were identified as promising biomarkers for the diagnosis and treatment of psoriasis and could be used for individualized treatments.
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Key words
Capase3,STAT2,pathogenesis,psoriasis,therapy
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