Impact of 18 F-Fluciclovine PET/CT Findings on Failure-Free Survival in Biochemical Recurrence of Prostate Cancer Following Salvage Radiation Therapy.

Ismaheel O Lawal,Charles Marcus,David M Schuster,Subir Goyal,Omotayo A Adediran,Vishal R Dhere,Shreyas S Joshi,Olayinka A Abiodun-Ojo,Viraj A Master,Pretesh R Patel,Bridget Fielder,Mark Goodman,Joseph W Shelton,Omer Kucuk,Bruce Hershatter,Raghuveer K Halkar,Ashesh B Jani

Clinical Nuclear Medicine（2023）

Cited 3|Views23

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Abstract

Findings on pre-SRT 18 F-fluciclovine PET/CT imaging, even when acted upon to optimize the treatment decisions and treatment planning, are predictive of post-SRT FFS in men who experience PCa recurrence after radical prostatectomy. A negative 18 F-fluciclovine PET/CT is most predictive of a lower risk of failure, whereas the presence of pelvic nodal recurrence portends a higher risk of SRT failure.

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Key words

F-18-fluciclovine PET/CT,biochemical recurrence,failure-free survival,prostate cancer,salvage radiation therapy

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