Inhibition of Pathologic Immunoglobulin E In Food Allergy by EBF2 and Active Compound Berberine Associated with Immunometabolism Regulation

Anish Maskey, Nan Yang,Monica Kim,Kamal Srivastava,Zixi Wang,Yanmei Shi,Yixuan Gong,Julie Wang,David Dunkin,Danna Chung,Jixun Zhan,Mingsan Miao,Hugh Sampson,Xiu-Min Li

Frontiers in Immunology（2023）

Cited 1|Views27

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Abstract

Food allergy is a significant public health problem with limited treatment options. As Food Allergy Herbal Formula 2 (FAHF-2) showed potential for a food allergy treatment, we further developed a purified version named EBF2 and identified active compounds. We investigated the mechanisms of EBF2 on IgE-mediated peanut (PN) allergy and its active compound, berberine, on IgE production.

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Key words

active compound berberine associated,food allergy

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