Whole-exome sequencing reveals genetic variants in low-risk and high-risk neuroblastoma

•Genetic variations in low-risk and high-risk NB patients were examined by WES.•The genetic variations found and compared with previous NB whole-exome sequencing studies in the cBioportal database.•Variants in ARID1A and NCOR2, related to chromatin remodeling, were commonly mutated in cBioportal and high-risk patients.•Candidate gene variations associated with chromatin remodeling, RAS pathway, cell proliferation, and DNA repair mechanism.