Safety of Direct Oral Anticoagulants for Gastrointestinal Hemorrhage in Patients With Nonvalvular Atrial Fibrillation: A Systematic Review and Meta-analysis of Real-world Studies.

Paraschos Archontakis Barakakis,Damianos G Kokkinidis,Weijia Li,Sanjana Nagraj,Spyros Peppas,Michail Kladas,Dimitrios Schizas,Panagiotis Korantzopoulos,George Ntaios

Journal of clinical gastroenterology（2022）

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Abstract

Our study shows that Apixaban was associated with a reduction in GIH risk compared with Dabigatran, Rivaroxaban and VKA, whereas Rivaroxaban was associated with an increase in GIH risk compared with both Dabigatran and VKA.

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