Age-related reference intervals for serum phytosterols in children by gas chromatography-mass spectrometry and its application in diagnosing sitosterolemia.

Mengyuan Wu,Zhou Pei,Weihua Sun,Hongjiang Wu, Yan Sun,Bingbing Wu,Wenhao Zhou,Feihong Luo,Wei Lu

Clinica chimica acta; international journal of clinical chemistry（2023）

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摘要

We established age-related RIs for five phytosterols in children based on an optimized GC-MS assay, providing a screening tool for the diagnosis of sitosterolemia in children.

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关键词

Cholesterol,Gas chromatography-mass spectrometry,Hypercholesterolemia,Phytosterol,Reference interval,Sitosterolemia

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