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Prolonged SARS-CoV-2 Infection and Intra-Patient Viral Evolution in an Immunodeficient Child.

Micheli Filippi,Mariene Ribeiro Amorim,Mariana Soares da Silva,Juliana Schons Gularte,Meriane Demoliner,Viviane Girardi,Vyctoria Malayhka de Abreu Goes Pereira,Alana Witt Hansen,Juliane Deise Fleck,Júlia Frohlich,Fernanda de-Paris,Grazielle Motta Rodrigues,Janaina Aparecida Risczik Arruda Correa,Elissandra Machado Arlindo De Mattos,Rodrigo Minuto Paiva,Caroline Deutschendorf,Frederico Soares Falcetta,José Luiz Proença Modena,Fernando Rosado Spilki

The Pediatric infectious disease journal（2023）

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摘要
In conclusion, we emphasize that genomic surveillance can be a useful tool to assess possible evolution signals in long-term patients.
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关键词
amino acid substitution,genomic surveillance,persistent infection,SARS-CoV-2
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