A simple genetic stratification method for lower cost, more expedient clinical trials in early Alzheimer's disease: A preliminary study of tau PET and cognitive outcomes.
Alzheimer's & dementia : the journal of the Alzheimer's Association（2023）
Abstract
Incorporating a PHS inclusion criterion represents a low-cost and accessible way to identify potential participants for AD clinical trials.
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Key words
Alzheimer's disease,clinical trials,polygenic hazard score,tau positron emission tomography
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