Impact of randomised w mel Wolbachia deployments on notified dengue cases and insecticide fogging for dengue control in Yogyakarta City.

Deployments of Mel-infected Aedes aegypti mosquitoes resulted in an 83% reduction in the application of perifocal insecticide spraying, consistent with lower dengue case notifications in wMel-treated areas. These results show that the Wolbachia intervention effect demonstrated previously in a cluster randomised trial was also measurable from routine surveillance data.