Serum soluble interleukin-7 receptor alpha levels are negatively correlated with the simultaneous activity of antineutrophil cytoplasmic antibody-associated vasculitis.

Taejun Yoon,Jung Yoon Pyo,Sung Soo Ahn,Jason Jungsik Song,Yong-Beom Park,Sang-Won Lee

Clinical and experimental rheumatology（2023）

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摘要

This study demonstrated that not only serum sIL-7Rα levels but also the populations of CD3+ and CD3+CD8+ T cells expressing m IL-7Rα were negatively correlated with simultaneous BVAS in patients with AAV. Therefore, we suggest that serum sIL-7Rα levels can be an additional and useful biomarker for assessing the simultaneous activity of AAV.

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关键词

soluble receptor, IL-7, antineutrophil cytoplasmic antibody, vasculitis, activity

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