Decline in the Age of Menarche in İstanbul Schoolgirls Over the Last 12 Years.

Tulay Guran,Didem Helvacioglu,Busra Gurpinar Tosun,Zehra Yavas Abali,Fahriye Alir,Yusuf Taha Arslan,Giasim Molla,Berk Sahin,Mehmet Emir Sayar,Zeynep Atay,Belma Haliloglu,Korcan Demir,Serap Turan,Seyhan Hidiroglu,Abdullah Bereket

Journal of clinical research in pediatric endocrinology（2023）

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摘要

The present study demonstrates a significant downward trend in the menarcheal age in Istanbul over the last decade. Our findings support a strong contribution of genetic factors and BMI on AAM.

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关键词

Puberty,Turkey,age at menarche,pubertal timing,secular trend

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