Regulation of the Inflammatory Response, Proliferation, Migration, and Epithelial-Mesenchymal Transition of Human Lens Epithelial Cells by the lncRNA-MALAT1/miR-26a-5p/TET1 Signaling Axis.

Yaru Hu,Xue Han,Yue Chen,Jinbiao Cai,Juan Li,Yuchen Fan,Jianfeng Wang,Shanglun Xie

Journal of ophthalmology（2023）

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摘要

The inflammatory environment and MALAT1 expression could be reciprocally induced in HLECs. MALAT1 may act as a ceRNA via the "sponge" miR-26a-5p and target TET1 to regulate the inflammatory response, proliferation, migration, and EMT processes in HLECs.

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human lens epithelial-mesenchymal cells,epithelial-mesenchymal cells,lncrna-malat

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