Trojan-horse silk fibroin nanocarriers loaded with a re-call antigen to redirect immunity against cancer.

Journal for immunotherapy of cancer(2023)

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摘要
Both SFNs-OVA and SFNs-CpG induce effective anticancer response through complementary mechanisms and show the efficacy of an innovative active immunotherapy approach based on the redirection of pre-existing immunity against cancer cells. This approach could be universally applied for solid cancer treatments if translated into the clinic using re-call antigens of childhood vaccination.
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关键词
Immunotherapy, Active,Lymphocytes, Tumor-Infiltrating,Melanoma,Translational Medical Research,Vaccination
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