The mechanistic and structural role of von Willebrand factor in endotoxemia-enhanced deep vein thrombosis in mice.

Seon Jae Choi,Courtney N Dwyer,Lindsy Rapkin,Matthew Cormier,Charles C T Hindmarch,Kate Nesbitt,Alison Michels,Wilma Hopman,Laura L Swystun,David Lillicrap

Journal of thrombosis and haemostasis : JTH（2023）

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摘要

We observe a key role for VWF in the pathogenesis of inflammation-associated venous thrombosis while providing a more comprehensive insight into the molecular interactions that constitute the architecture of venous thrombi.

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关键词

animal models,image cytometry,thromboinflammation,venous thrombosis,von Willebrand factor

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