Genome-wide association study of the age of onset of type 1 diabetes reveals HTATIP2 as a novel T cell regulator.

Christopher J. Cardinale,Xiao Chang,Zhi Wei,Hui-Qi Qu,Jonathan P. Bradfield,Constantin Polychronakos,Hakon Hakonarson

Frontiers in immunology（2023）

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摘要

This study implicates HTATIP2 as a new type 1 diabetes gene acting via T cell regulation. Larger population sample sizes are expected to reveal additional loci.

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关键词

HTATIP2/TIP30,RNA-seq,T cells,gene expression,genome-wide association study (GWAS),pediatrics,type 1 diabetes

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