C-reactive protein interacts with amphotericin B liposomes and its potential clinical consequences.

experiments are suggestive of a complexation between CRP and liposomes in plasma. Interpretation of CRP values following administration of AmBisome might be impaired due to this complexation. formation of complexes between liposomes and CRP might contribute, or even lead, to intravascular microembolisation. Similar effects have been described following the administration of Intralipid and other phosphocholine-containing liposomes.