Real-world impact of antifibrotics on prognosis in patients with progressive fibrosing interstitial lung disease.

Takayuki Niitsu,Kiyoharu Fukushima,Sho Komukai,So Takata,Yuko Abe,Takuro Nii,Tomoki Kuge,Shinichi Iwakoshi,Takayuki Shiroyama,Kotaro Miyake,Kazuyuki Tujino,Satoshi Tanizaki,Kota Iwahori,Haruhiko Hirata,Keisuke Miki,Masahiro Yanagawa, Noriyuki Takeuchi,Yoshito Takeda,Hiroshi Kida,Atsushi Kumanogoh

RMD open（2023）

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摘要

This is the first real-world study to show that antifibrotics improve the FVC decline in PF-ILD. However, among patients with non-IPF, we found no significant difference in mortality between those with and without antifibrotics. Future studies must clarify whether antifibrotics improve the prognosis of non-IPF.

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关键词

fibroblasts,pulmonary fibrosis,therapeutics

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