An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure (RMP) for the quantification of gabapentin in human serum and plasma.

Linda Salzmann,Janik Wild,Neeraj Singh,Tobias Schierscher,Franziska Liesch,Friederike Bauland,Andrea Geistanger,Lorenz Risch,Christian Geletneky,Christoph Seger,Judith Taibon

Clinical chemistry and laboratory medicine（2023）

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摘要

This analytical protocol for gabapentin, utilizing traceable and selective qNMR and ID-LC-MS/MS techniques, allows for the standardization of routine tests and the reliable evaluation of clinical samples.

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关键词

ID-LC-MS/MS,gabapentin,qNMR,reference measurement procedure,standardization,traceability

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