Multipotent mesenchymal stromal cells as treatment for poor graft function after allogeneic hematopoietic cell transplantation: A multicenter prospective analysis.

Sophie Servais,Frédéric Baron,Chantal Lechanteur,Laurence Seidel,Etienne Baudoux,Alexandra Briquet,Dominik Selleslag,Johan Maertens,Xavier Poire,Wilfried Schroyens,Carlos Graux,Ann De Becker,Pierre Zachee,Aurélie Ory,Julie Herman,Tessa Kerre,Yves Beguin

Frontiers in immunology（2023）

Cited 0|Views34

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Abstract

In conclusion, a single i.v. infusion of BM-derived MSC from third party donor seemed to improve hematological function after alloHCT, although spontaneous amelioration cannot be excluded. Comparative studies are warranted to confirm these encouraging results.

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Key words

allogeneic stem cell transplantation,cytopenia,mesenchymal stromal cells,poor graft function,thrombocytopenia

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