Skeletal "Superscan" With C-11-Methionine PET/CT in Polycythemia Vera

C-11-methionine PET/CT for parathyroid adenoma localization on a 60-year-old woman known with polycythemia vera revealed highly methionine-avid red bone marrow, an uptake pattern that has previously been described in hematological disease such as multiple myeloma. An equivalent skeletal "superscan" pattern in polycythemia vera has been described with other PET tracers, but this case illustrates that this pattern can be seen with C-11-methionine PET/CT as well and can be added to the list of potential pitfalls.