Extracellular vesicles of human diabetic retinopathy retinal tissue and urine of diabetic retinopathy patients are enriched for the junction plakoglo bin protein.

Jason Mighty,Alfonso Rubio-Navarro,Cui Shi,Jing Zhou,Miguel Flores-Bellver,Søren Heissel,Onyekwere Onwumere,Linda Einbond,Rajendra Gharbaran,Daniel S Casper,Alberto Benito-Martin,Stephen Redenti

Frontiers in endocrinology（2022）

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摘要

The absence of JUP in healthy urinary EVs provide the basis for development of a novel Diabetic Retinopathy biomarker, potentially facilitating diagnosis.

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关键词

JUP,diabetic retinopathy,extracellular vesicle (EV),proteomics & bioinformatics,retina,urinary EVs

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