The diagnostic and prognostic value of IgG and IgA anti-citrullinated protein antibodies in patients with early rheumatoid arthritis.

Daniela Sieghart,Christian Konrad,Sascha Swiniarski,Helmuth Haslacher,Daniel Aletaha,Günter Steiner

Frontiers in immunology（2022）

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摘要

Specificity of ACPA assays should be adjusted to reduce the risk of misclassification and a false positive diagnosis. Determination of ACPA IgA might provide important prognostic information concerning therapeutic responses.

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关键词

IgA autoantibodies,anti-citrullinated protein autoantibodies,cyclic citrullinated peptide,diagnostic performance,rheumatoid arthritis

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