Research progress and quality markers prediction analysis of Dysosma versipellis

Traditional Medicine Research(2023)

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Abstract
Dysosma versipellis is the rhizome of Bajiaolian in Berberaceae. It is a unique medicinal plant in China and it was the first to be recorded in Shennong's Classic of Materia Medica (unknown author, 25–220 C.E.). It has complex chemical components as well as complex, pharmacological and toxicological effects are extensive. Based on the recent research progress, the chemical constituents, pharmacological activities and toxicological effects of Dysosma versipellis were summarized. Combined with the core concept of quality markers of traditional Chinese medicine, the prediction and analysis were carried out from the aspects of phytogenetics and the source pathway of specific chemical constituents, traditional medicinal properties, traditional efficacy, chemical composition measurability, blood components, and pharmacokinetics, in order to provide reference for further study of Dysosma versipellis.
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Key words
Dysosma versipellis,lignans,flavonoids,chemical composition,pharmacological activity,toxicological effect,quality marker,podophyllotoxin,kaempferol,quercetin
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