异基因造血干细胞移植术后EB病毒相关淋巴组织增生性疾病病例报道

International Journal of Virology(2022)

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Abstract
报道1例异基因移植后EB病毒(epstein-barr virus,EBV)相关的淋巴组织增生性疾病,探讨临床特征、病理诊断、鉴别诊断及预后治疗。患者女性,异体基因移植术后51 d,发热体温38.1 ℃,双侧颈部及左侧腋窝淋巴结均肿大,左侧腋窝淋巴结穿刺活检,显微镜下见淋巴细胞弥漫增生,小-中等大小,见散在异型大细胞。免疫组化提示:EBV相关淋巴组织增生性疾病。诊断过程需要鉴别EBV相关淋巴瘤,如霍奇金淋巴瘤,NK/T淋巴瘤等。
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Key words
Epstein-barr virus,Post-transplant lymphoproliferative disorder,Allogene,Clinicopathologic features
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