Implantable and Bioresorbable Nanostructured Fluorescence Sensor for In vivo pH Monitoring.

Martina Corsi,Alessandro Paghi,Stefano Mariani,Giulia Golinelli,Aline Debrassi,Gabriella Egri,Giuseppina Leo,Eleonora Vandini,Antonietta Vilella,Lars Dähne,Daniela Giuliani,Giuseppe Barillaro

IEEE SENSORS（2022）

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摘要

Here we report on a bioresorbable fluorescence sensor for in vivo pH monitoring. The sensor leverages a nanometer-thick multilayer stack of polyelectrolytes labelled with a pH-insensitive fluorophore conformably deposited within a porous silica membrane-thickness of a few micrometers-to increase fluorescence intensity up to 600 times and enable reliable measurements through skin.

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关键词

Bioresorbable sensor,biomedical implant,in vivo pH sensing,wireless sensor,fluorescence sensor,porous silicon (PSi),layer-by-layer (LbL)

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