Anti-inflammatory effects of β-FNA are sex-dependent in a pre-clinical model of LPS-induced inflammation.

Stephanie Myers,Kelly McCracken,Daniel J Buck,J Thomas Curtis,Randall L Davis

Journal of inflammation (London, England)（2023）

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摘要

These findings provide novel insights into the sex-dependent anti-inflammatory effects of β-FNA and advance this agent as a potential therapeutic option for reducing both neuroinflammation an intestinal inflammation.

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关键词

Chemokine,Cytokine,Neuroinflammation,Neuroprotective,Nuclear factor-κB,Opioid,Peripheral inflammation,β-funaltrexamine

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