Rapid metabolic reprogramming mediated by the AMP-activated protein kinase during the lytic cycle of Toxoplasma gondii

Yaqiong Li,Zhipeng Niu,Jichao Yang,Xuke Yang,Yukun Chen,Yingying Li,Xiaohan Liang,Jingwen Zhang,Fuqiang Fan,Ping Wu,Chao Peng,Bang Shen

Nature Communications（2023）

Cited 1|Views25

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Abstract

Efficient metabolic regulation is key for parasite growth. Here, the authors report that Toxoplasma alters its AMPK phosphorylation during the lytic cycle, which reprograms parasite’s metabolism to ensure metabolic needs at different stages are met.

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