Rejection in patients with simultaneous pancreas-$$$kidney transplants- an immunologic Pas de Deux
The American Journal of the Medical Sciences(2023)
Abstract
chronic hyponatremia without neurologic impairment, slow increase of 4-6 mmol/L in a 24-hour period is preferred to avoid osmotic demyelination syndrome.Conclusion: Our patient displayed multifactorial etiology for hyponatremia.She had a history of chronic hyponatremia stemming from HCTZ use and undiagnosed liver cirrhosis.But aggravation of hyponatremia to the range of 98 mmol/L was likely due to added gastrointestinal and cutaneous losses with excessive water consumption.Also, SIADH from hospital acquired pneumonia triggered a recurrence of hyponatremia.Cautious management cannot be overstated to avoid neurologic complications.
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Key words
rejection,immunologic pas,pancreas-$$$kidney
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