A new FRDA mouse model [ Fxn null :YG8s(GAA) > 800] with more than 800 GAA repeats.

Ester Kalef-Ezra,Fred Jonathan Edzeamey,Adamo Valle, Hassan Khonsari, Paula Kleine, Carlo Oggianu,Sahar Al-Mahdawi,Mark A. Pook,Sara Anjomani Virmouni

Frontiers in neuroscience（2023）

引用 2|浏览11

暂无评分

摘要

These studies provide a detailed characterization of the GAA repeat expansion-based YG8JR transgenic mouse models that will help investigations of FRDA disease mechanisms and therapy.

查看译文

关键词

FRDA,FXN,Friedreich’s ataxia,GAA repeat,Y47JR,YG8JR,frataxin,mouse model

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要